In 2013, Gabbani released "I dischi non-si suonano" and "Clandestino" as singles from his debut studio album.

The following year, he was announced as a competitor in the newcomers section of the Sanremo Music Festival 2016 with the song "Amen", which went on to win the competition.

[4] The song was released as the lead single from his second studio album on 27 November 2015, and was certified platinum by the Federation of the Italian Music Industry.

In 2016, Gabbani composed the soundtrack of Italian comedy film Poveri ma ricchi, directed by Fausto Brizzi.

[6] Gabbani returned to the Sanremo Music Festival the following year, winning in the "Big Artists" section with the song "Occidentali's Karma".

On 4 May 2019, Gabbani released "È un'altra cosa", the first single from his fourth studio album, Viceversa.

[13][5] On 3 September 2021, Gabbani released "La rete", serving as the lead single of his upcoming fifth studio album.