Londonio trained as a painter under Ferdinando Porta and Giovanni Battista Sassi in Milan, but traveled to Rome and Naples.

An example, of this poorly conserved art form that still exists is a nativity scene on cut wooden shapes for the church of San Marco in Milan.

The effect is a cheaper version of the naturalistic Sacri Monti scenes, which had been painted stucco statuary.

It also can be seen as a cross between the holy scenes described above, and the theatrical set pieces, for example, those needed for the newly founded La Scala theater.

The work at San Marco prompted Empress Maria Theresa of Austria appointed Londonio as art designer for La Scala.