Francesco Manno (20 December 1754 – 18 June 1831) was an Italian painter and architect of the Neoclassical style.

Born at Palermo, where he was originally a goldsmith, but later devoted himself to painting, working along his older brothers, the painters Antonio and Vincenzo Manno.

then in the studio of Francesco Preziado de la Vega.

On 13 July 1794 he became a member of the Accademia dei Virtuosi del Pantheon.

Favored by Pope Pius VI, Manno was appointed Painter of the Sacred Apostolic Buildings in 1800.