He was the member of Primavera under-20 team[2] and in 2002 made his professional debut with Pro Patria of Serie C1, where he was sent on loan for a season.
On 1 July 2004, he returned to Parma, playing 21 games (9 in the UEFA Cup, 1 in the Coppa Italia, and 1 in the relegation playoffs) without scoring any goals; however noted by FC Lokomotiv Moscow, that signs him on loan for the 2005 Russian season.
Atalanta Bergamo was relegated from Serie A in May 2010 and had sold numbers of players to AlbinoLeffe in previous seasons.
In May 2012, Atalanta received two penalty points and a €25,000 fine as several players, including Ruopolo, had been accused of match fixing.
[10] During the "Festival International Espoirs de Toulon et du Var" in 2003, Ruopolo scored one goal against Portugal in the final of the tournament.