Francis Asekhame Alimikhena (born 20 September 1947) is a former Senator of the Federal Republic of Nigeria from Edo State.

[7][10][11] He is also a member of Knight of Saint Mulumba (KSM) and was given a respected traditional title as the OKHASO of wappa Wanno Kingdom by the Afemai people.

[10] In 2007, Alimikhena joined politics by contesting for the Edo North senatorial seat under the platform of Peoples Democratic Party but lost.

[12] On 19 December 2014, Alimikhena emerged as the senatorial candidate of the All Progressives Congress (APC) in a heated party primary election at Edo state.

[13] Alimikhena was elected to the Senate of the Federal Republic of Nigeria as the All Progressives Congress candidate from Edo North in March 2015.

[15] Alimikhena has sponsored several bills[citation needed] in the Senate: In the 25 February 2023, Edo North senatorial district National Assembly election, he was defeated by Adams Oshiomhole.

[5] Amid the 21 September 2024 poll, Francis Alimikhena dumped Peoples Democratic Party, and rejoined All Progressives Congress,[20][21] despite accusing them of "injustice" two years ago.