A variation of Nuke named Will Simpson appeared in the first and second seasons of Marvel's Netflix television series, Jessica Jones, portrayed by Wil Traval.

Nuke largely disappeared following his apparent death in Daredevil #233, although his origin was explored and touched upon in issues of Captain America and Wolverine.

It was not until Grant Morrison's New X-Men, when it's revealed Nuke was involved in the Weapon Plus program, that the character made a return in subsequent stories.

The disturbed son of a wealthy, abusive, alcoholic, upper-class woman in Ohio, Frank soon developed an unhealthy affection for his babysitter, the only real maternal figure in his life.

The young woman, who was harboring feelings for his father Charles Simpson, capitalized on Frank's affection and talked the boy into killing his mother.

He then allowed Frank to escape, testing his work with a village of peasants, who, seeing an American soldier, tried to soothe his anger and convince him to spare them, shouting the "No V.C.!"

[2] At some time during the war, Nuke was inducted into the final part of the Project Homegrown, the Weapon VII programs, that turned him into a partial cyborg with a subdermal mesh able to deflect bullets, and a second heart that, working in conjunction with some (placebo) pills, controlled his aggression, leaving him addicted as well.

[8] During Norman Osborn's tenure as the head of the American peace-keeping organization H.A.M.M.E.R., the character uses the "Scourge" alias and added to the Thunderbolts,[9] and is demoted from the position of team leader.

While at a bar in British Columbia, Wolverine's adamantium skull headbutts Nuke to spread the word that he spared him while also getting the information on who placed the bounty on him.

Aside from his strength, Nuke's body is considerably more resistant to physical injury than that of an ordinary human; even the arcane nerve strikes Daredevil learned during training by his sensei, Stick, have no effect.

Nuke is the victim of decades of systematic physical and psychological conditioning at the hands of various individuals working for the United States government.

Also in his first appearance in Daredevil, Nuke was equipped with a monstrous multi-barrelled assault rifle which, in addition to being able to fire massive volleys of bullets, fragmentation grenades, and rockets, was also (due to mechanisms left unexplained) able to "keep count" of the casualties inflicted.

[volume & issue needed] Nuke, renamed William "Will" Simpson, appears in Jessica Jones, portrayed by Wil Traval.

[30] As of the second season, he has begun using an inhaler, spying on Walker,[31] and discovered IGH is targeting Jones before he is attacked and killed by Alisa Campbell.