[1] She made her acting debut in 1995 on the Canal 13 telenovela Amor a domicilio [es], but she achieved greater popularity the following year when she portrayed Cathy Winter, the protagonist of Adrenalina.

In 1999, she starred with Jorge Zabaleta in the TV series Cerro Alegre, playing Beatriz León Thompson, a young upper-class woman in the city of Viña del Mar.

In 2005 she appeared in the film The Last Moon by director Miguel Littín, where she was a castmate of Alejandro Goic and Tamara Acosta.

In December 2015, after being away from television, the morning show Bienvenidos, led by Tonka Tomicic and Martín Cárcamo, recruited her to be a panelist.

In an unprecedented event in the television industry, Merino, with a contract on Canal 13, managed to work on two channels at the same time.

On 9 April 2014, the SQP program discussed the performance of singer Ana Tijoux at the Lollapalooza festival, where some young people in the audience shouted cara de nana (housemaid face) to the artist.