[3] She worked for the United States Geological Survey,[1] and the United States National Museum (now the National Museum of Natural History) from 1911 to 1929[4] with the title of "paleontologic draftsman".
She was the daughter of German immigrants, her mother was Sophia Ailer (née Seitz),[6] and her father was a war veteran (1st Maryland Cavalry in the Union Army during the American Civil War) and a visual artist, Louis Wieser (1836–1904).
[1][7] Her younger sister Florence Wieser (1877–1949) also worked as an illustrator and artist at the United States Geological Survey.
[1] She served as an artist and illustrator to several departments and for several people, including Ray S. Bassler,[3] and Charles Doolittle Walcott.
[4][9] Wieser used a combination of a microscope and drawing, camera lucida,[10] to record fossils that were millions of years old,[11] and was recognized for her ability to capture details of fossils by drawing rather than relying on photography.