Francisco is an unincorporated community in northern Jackson County, Alabama, United States.

It is located on Alabama State Route 65, 19.1 miles (30.7 km) northwest of Skyline.

Francisco is named in honor of Francisco Rice, who served in the Confederate Army and as a member of the Alabama Senate.

[2] A post office operated under the name Francisco from 1875 to 1957.

This Jackson County, Alabama state location article is a stub.