Francisco Carlos Bustillo Bonasso (born April 1, 1960) is a Uruguayan diplomat who served as Minister of Foreign Relations of Uruguay from July 6, 2020 to November 1, 2023.

[1] Bustillo entered the Ministry of Foreign Affairs of Uruguay by merit competition on January 1, 1986.

On April 1, 2005, he was appointed by President Tabaré Vázquez as Ambassador Extraordinary and Plenipotentiary of Uruguay in Argentine Republic, a position he held for 5 years.

[4] In late June 2020, it was confirmed that Bustillo would replace Ernesto Talvi as Minister of Foreign Relations of Uruguay, who presented his resignation,[5] stating "It has been a privilege to serve the citizens of Uruguay from the Foreign Ministry at this time in which it was necessary to face extremely complex challenges".

[8] In September 2020, UN Watch exposed Uruguay’s vote for a UN resolution that singled out Israel alone in the world for supposedly violating women’s rights.