[3] After entering the priesthood, Marroquín became a professor at the University of Osuna where he met Bishop García de Loaisa, an adviser to Emperor Charles V.[4] Marroquín became a priest in the Spanish royal court.

[5] After first arriving in Mexico, he traveled onwards to Guatemala with Alvarado, in May 1528.

[6] On April 8, 1537, he was consecrated bishop by Juan de Zumárraga, Archbishop of Mexico, with Juan Lopez de Zárate, Bishop of Antequera, Oaxaca serving as co-consecrator.

[7] Marroquín founded the School of Saint Thomas in 1559 (now the University of San Carlos of Guatemala) as part of his efforts to educate the native people.

[8] The Universidad Francisco Marroquín in Guatemala City is named for him.