Juan López de Zárate (June 24, 1490 – September 10, 1555) was a Spanish Roman Catholic prelate who served as the first Bishop of Antequera, Oaxaca (1535–1555).

[1] Juan López de Zárate was born in Oviedo, Spain.

[2] On June 21, 1535, he was appointed by Pope Paul III as Bishop of Antequera, Oaxaca.

[1][2] On April 8, 1537, he was consecrated bishop by Don Juan de Zumárraga, Archbishop of Mexico.

[2] While bishop, he was the principal consecrator of Martín Sarmiento de Osacastro, Bishop of Tlaxcala (1549) and the principal co-consecrator of Francisco Marroquín Hurtado, Bishop of Santiago de Guatemala (1537)[2] Zárate died on September 10, 1555,[1][2] while in attendance at the First Mexican Provincial Council.