[1] Francisco de la Serna was born in Huanuco, Peru in 1568 and ordained a priest in the Order of Hermits of Saint Augustine on 9 June 1596.
[2][3] On 17 December 1635, he was appointed during the papacy of Pope Urban VIII as Bishop of Paraguay.
[2][3] On 14 June 1638, he was appointed during the papacy of Pope Urban VIII as Bishop of Popayán.
[1][2][3] On 19 January 1645, he was selected by the King of Spain and confirmed by Pope Innocent X on 21 August 1645 as Bishop of La Paz.
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