Frank Edward Guernsey (October 15, 1866 – January 1, 1927) was a U.S. Representative from Maine.

Guernsey married Josephine Frances Lyford on June 16, 1887, in Vinal Haven, Maine.

[1] Guernsey was elected treasurer of Piscataquis County, Maine in In September, 1890, and he was re-elected twice, serving in this office until December 31, 1896.

Guernsey was elected as a Republican to the Sixtieth Congress to fill the vacancy caused by the death of Llewellyn Powers.

Guernsey was reelected to the Sixty-first and to the three succeeding Congresses and served from November 3, 1908, to March 3, 1917.