He has recorded and worked with several high profile musicians including Robi "Draco" Rosa, Tool, Gordon Gano, PJ Harvey, Tommy Stinson, Nena, Frank Black of The Pixies, Neil Young, Perry Farrell and Cheetah Chrome of The Dead Boys.

The band featured Ferrer on drums along with Jonathan Lacey on vocals and guitar, and bassist Perry Bottke.

In July 2006, Frank Ferrer joined Guns N' Roses during their European Tour to replace Bryan "Brain" Mantia, who had returned to the United States when his wife had a child.

He took part in the reunion Not in This Lifetime... Tour, featuring classic-era members Slash and Duff McKagan, which circled the world from 2016 to 2019.

[3][4] In 2019, Ferrer formed the hard rock band PSSR with singer/guitarist Eric J, bassist Brett Bass, and lead guitarist Rob Bailey, and released their first single "Busted".

According to an April 2023 article in Business Insider,[6] Ferrer has been refusing to make necessary repairs and disrupting the lives of his tenants.

According to the article, the property was declared a public nuisance by the city of La Quinta and remains the subject of an open investigation.