Frank Edward Hankinson (April 29, 1856 – April 5, 1911) was an American third baseman in the early years of Major League Baseball.

He played for the Chicago White Stockings (1878–1879), Cleveland Blues (1880), Troy Trojans (1881), New York Gothams (1883–1884), New York Metropolitans (1885–1887), and Kansas City Cowboys (1888).

Born in New York City, Hankinson was, for the most part, a third baseman, but over the course of his career he played at every position except catcher; he pitched in 32 games, starting 28 of them.

He was 16–12 with a solid 2.50 ERA in 2662⁄3 innings pitched in his career.

In a 10-season career, Hankinson batted .228 with 13 home runs and 344 RBIs.