Frank Cotter Henderson OBE (8 March 1911 – 21 July 1969) was an Australian agriculturalist and public servant.

He held senior positions in the government of the Territory of Papua and New Guinea and served as an official member of the Legislative Council and House of Assembly.

Following the Japanese invasion, he helped evacuate civilians, sailing from Talasea to Cairns in Australia.

[2] In 1951 he was appointed head of the Division of Plant Industry, moving to Port Moresby the following year.

He was promoted to Assistant Administrator (Economic Affairs) in 1966, also becoming Leader of Government Members in the House of Assembly.