Infante began his music career playing guitar in hard rock and electric blues groups such as The Elegant End and World War III.
After sessions for the band's 1980 album Autoamerican, Infante sued the group for his alleged minimal involvement in the recording (which would affect his royalties), but the matter was settled out of court.
Throughout his time with Blondie, Infante contributed to writing a handful of their songs, including "Victor" and "I Know but I Don't Know", plus a demo from the Parallel Lines sessions titled "Underground Girl".
Iggy Pop's German compilation Nuggets in 1999 and UK box set Where The Faces Shine in 2009 both feature live tracks with Infante on guitar.
[9][10] In December 2018, he was recruited by Divinyls guitarist Mark McEntee to participate in an Australian reunion tour, intended to commence in February 2019 but cancelled on the 6th of that month.