He was formerly the Head Coach of the renowned Suburban and Foxcatcher Swim Clubs in Philadelphia from 1966 to 1978, where he led his teams to consecutive Eastern USA Championships.

The Suburban Swim Club team were the Eastern USA Champs from 1969 to 1976, and finished in the Top 10 in the National AAU Championships from 1968 to 1976.

Returning to the place of his birth, he accepted an offer to coach the Yale University Men's Swimming team, beginning in September 1980.

He also served as head coach of the Women's team from 1980 to 2010, impressively leading them to five Ivy League Championships.

He also coached NCAA All Americans Lisa O'Dell, Jason Rosenbaum, Missy Dallyrimple, Suzanne Heiser and George Gleason.

[6] After his retirement from coaching Yale in 2010, he returned to the Philadelphia area and remained active in the Pennsylvania swimming community.

He volunteered as an assistant coach at his alma mater Villanova, Swarthmore College, La Salle University and the Shipley School.

[6] Keefe last resided in Downington, Pennsylvania, not far from Newton Square where he coached the Foxcatcher Swim Club.