Frank Lionel O'Keefe, AM (6 October 1912 – 21 April 1989) was an Australian politician.

Born in Gunnedah, New South Wales, he attended state schools before becoming a farm machinery distributor and oil merchant.

In 1961 he was elected to the New South Wales Legislative Assembly for Liverpool Plains, representing the Country Party; he transferred to Upper Hunter in 1962, which he held until 1969.

[1] In that year he was elected to the Australian House of Representatives as the member for Paterson.

This article about a National Party of Australia politician is a stub.