Administered by the United States Environmental Protection Agency, which regulates the introduction of new or already existing chemicals, the Act amends and updates the Toxic Substances Control Act (TSCA) that went into force in 1976.

Senators David Vitter and Frank Lautenberg introduced a TSCA reform bill as S. 1009[1] on May 22, 2013, co-sponsored by a number of other senators at the United States House Energy Subcommittee on Environment and Economy.

[5] Congress passed a reconciled version of the reform bill with bipartisan support in June 2016.

On Wednesday, June 22, 2016, President Barack Obama signed the bill into law.

[6] Lawmakers and industry groups were largely supportive of the new law, while environmental advocates offered more mixed reactions.