[1] Wesley was born in Azamgarh, Uttar Pradesh into a fifth generation Christian family of Hindu and Muslim descent.
[1] After two years (1958-1960) in the United States at the Art Institute of Chicago, Wesley returned to India.
[2] Wesley made art based on both biblical and secular themes.
He used water colours, oil paintings, miniatures and wooden carvings.
[3] In 1993, Naomi Wray published a book titled "Frank Wesley: Exploring faith with a brush" about his Christian work.