Continuing east, Franklin is the southern border of Whitley Heights,[2] and turns into a major east–west thoroughfare in the Hollywood Hills.

The first house in the Hollywood area, built by Tomás Urquidez in 1854, was at the intersection of what would become Franklin and Outpost Drive.

Hollywood Tower, often cited as the inspiration for the Twilight Zone Tower of Terror attractions at Disney parks in Florida, California, Paris and Tokyo,[5] is located one block west of Franklin and Gower Street, an intersection that has been cited as one of the better places to photograph the Hollywood Sign.

[6] Château Élysée, a former residential apartment house for movie stars and now the Church of Scientology Celebrity Centre, is located in the Franklin Village neighborhood at Franklin and Bronson Avenue,[7] as is Upright Citizens Brigade Theatre[8] and Villa Carlotta.

Shakespeare Bridge is located further east, near the intersection of Franklin and St. George Street in the Franklin Hills area of the Los Feliz district of Los Angeles.