In spite of his background, Křižík managed in 1866 to study engineering at the Technical University of Prague ČVUT.

Křižík is considered the pioneer of practical electrical engineering and in electrification of Bohemia and Austro-Hungarian empire.

The restored and fully functional patented arc lamp with automated electrode adjustment can be viewed at the Museum of Plzeň.

In 1884 Křižík set up his own company building city lighting, tramway lines, street cars, power stations, and various electric equipment.

František Křižík built the first electrified railway in the Austro-Hungarian empire from Tábor to Bechyně in 1903.