Here he managed the castle library, met with the Liběchov intellectual society, wrote poetry and together with the sculptor Václav Levý he took part in producing relief sculptures at the caves nearby (the so-called Klácelka).
After the overthrow of the Prague uprising he once more returned to Brno, after a short stay in Česká Třebová, to work on the Moravian Weekly once more.
Klácel became involved with (and gave information in the Moravian News) club activities (National Union of St. Cyril and Methodius), and the Bohemian-Moravian Brotherhood (Jan Ivan Helcelet, Hynek Hanuš, Božena Němcová and her husband) was supposed to become a basis for the materialisation of his ideas of humanitarianism, but his aims foundered, and this affected Klácel's friendship with Němcová.
Although Klácel industriously translated, published and wrote a number of popular scientific handbooks, American reality did not meet with his imaginations and he fell into serious financial difficulties.
In his version of Goethe's epos Reynard the Fox (1845) and the anthology Bájky Bidpájovy (1846 and 1850) he used animal allegories in order to critically portray contemporary society.
This Augustinian friar in Brno, an excellent teacher, author of a number of poetic and philosophical works, natural science researcher, journalist, unselfish and loving man František Matouš Klácel was one of the leading revivalists in Moravia and active members of political life during the revolutionary period of 1848–49.
A road is named after him in Brno – Masarykova Quarter, and from 1978 a memorial stone with his portrait by Milada Orthová has been on the side of number 1 Mendlovo Square.