Franz Christoph Anton, Count of Hohenzollern-Sigmaringen (16 January 1699 in Haigerloch – 23 November 1767 in Cologne) was a member of the House of Hohenzollern.
He was canon of several cathedral chapters and also first minister of the Prince-Archbishopric of Cologne under Archbishop Clemens August.
He was the son of Count Franz Anton of Hohenzollern-Haigerloch and his wife Anna Maria Eusebia of Königsegg-Aulendorf.
His elder brother Ferdinand Leopold was also at various times canon of several cathedral chapters, first minister of Cologne, and ruling Count of Hohenzollern-Haigerloch.
He also served as Hofmeister, war councillor, governor of the Diocese of Strasbourg and chancellor of the University of Cologne.