Franz Ignaz Oefele (26 June 1721, Posen - 18 September 1797, Munich) was a German painter, etcher, and miniaturist.
His father was a watchmaker from Bavaria, who died before Oefele was a year old, so he was raised by an uncle in Landsberg am Lech who operated a brewery.
After eight years in Italy, he returned to Munich and became the court painter for Maximilian III Joseph, Elector of Bavaria.
In 1770, he helped to create and was appointed the first Professor of Drawing at what would later become the Academy of Fine Arts, with an annual salary of 100 Gulden.
His older cousin was the historian and librarian, Andreas Felix von Oefele.