On January 17, 2025, Frasier was canceled by Paramount+; however, CBS Studios has announced that they plan to shop the show to other outlets, such as Prime Video or Hulu.

In order to do so, Frasier takes a professorship at Harvard University, buys and moves into Freddy's apartment building and, with the help of his family, friends, and his new colleagues, starts to embark on his "third act".

Accompanied by his nephew David, Frasier Crane returns to Boston after his father's funeral and his breakup from Charlotte to give a guest lecture at Harvard University as a favor to an old college classmate of his, Alan Cornwall.

Eventually, Freddy admits that Eve was the girlfriend of John's father, a fellow firefighter who fell in the line of duty, and that he did not attend Martin's funeral due to the mental anguish of his survivor's guilt.

Frasier quickly decides to accept the job at Harvard and buys Eve and Freddy's apartment building to be a part of his son's life.

Grammer said he "gleefully" anticipated "sharing the next chapter in the continuing journey of Dr. Frasier Crane" as he had "spent over 20 years" of his "creative life on the Paramount lot".

[9] In March 2023, it was announced that Bebe Neuwirth would be reprising her role as Frasier's ex-wife Lilith Sternin in the revival.

[21][16] On January 30, 2023, Greenberg shared a picture of a script page from a table read which gave some more information about the show.

The website's consensus reads: "With Kelsey Grammer safely back in the role he was born to play, Frasier scores as comfort viewing even if it can't quite compare to the classic original series.