From 1915 to 1917 Fulton won 17 consecutive matches (14 by KO) including stopping Charley Weinert, Terry Kellar, and Arthur Pelkey.

By the end of 1917 Fred Fulton added knockout wins against Sam Langford and Gunboat Smith, solidifying his position as the number one contender.

Fulton's dreams of obtaining a title fight were hastened when he was brutally KO'd by future heavyweight champion Jack Dempsey in 18.6 seconds of the first round on July 27, 1918.

From then until July 1920, Fulton would win 19 consecutive bouts including stoppages over such contenders as John Lester Johnson, Frank Moran, Jack Thompson, and Willie Meehan.

Fulton's boxing ability continued to show a rapid decline as he lost or drew in over half of his remaining fights, including several against rising top contenders as Floyd Johnson, George Godfrey, and Jack Renault.