Frederick Ernest Weiss FRS[1] FLS VMH (2 November 1865 – 7 January 1953) was an Anglo-German Botanist.

[2] Weiss was educated at the Owens College (later Victoria University of Manchester), and earned a doctorate in botany (DSc) from the University of London in July 1902.

[3] Weiss was Professor of Botany at the Victoria University of Manchester.

In 1913, Weiss succeeded Sir Alfred Hopkinson as vice-chancellor, initially on a temporary basis until a suitable candidate was found.

He continued as Professor of Botany during his tenure as vice-chancellor and in 1915 he was succeeded by Sir Henry Alexander Miers, mineralogist and former principal of the University of London (1908–1915).