The Society's original premises on George Street were destroyed during the Manchester Blitz (around January 1941), at which time its library comprised more than 50,000 volumes as well as historic artefacts, portraits, and archives.
[8] Membership is open to anyone aged over 16 years and lectures are held both in person at venues in Manchester City Centre, and (since 2020) online.
[8] The Society operates from an office situated in Colony Jactin House, Ancoats, Manchester, and has three permanent staff.
Honorary Members have included Stephen Hawking, William Thomson, Lord Kelvin, Robert Bunsen, Sergey Kapitsa, Dmitri Mendeleev, Sir Cyril Hinshelwood, Dame Kathleen Ollerenshaw, Jöns Jacob Berzelius and John Mercer.
It contains the transactions of the society (most notably the text of many recent lectures) and is distributed to members and to similar institutions and libraries throughout the world by subscription.
Several medallists have had Manchester and University of Manchester/Owens College connections with the Departments of Physics and Astronomy, Chemistry and Engineering.