His most notable works include The Origin of Life and The Marriage Guide, both of which focus on teaching healthy sexual practices and behavior, as well as proper knowledge of the reproductive processes and management of diseases.

[4] Prior to the release of his 1860 health manual The Marriage Guide, which openly discussed such things as the benefits of aphrodisiacs, legal prostitution, and multiple orgasms in females,[5] people were rarely exposed to such information.

Some of his "home remedies" for impotence, for instance, included the use of Cannabis indica (marijuana), a deep tissue groin massage/shampoo, or a suctioning machine of Hollick's own creation, which he claimed was able to bring back an erection to any dysfunctional man.

[6] However, the first charges were eventually dropped due to witnesses dismissal of the mannequin as obscene, but rather informational, which only reaffirmed the widely held belief that Hollick's teachings provided a fresh, welcoming view of sex.

[11] Even though charges still remained against Hollick, the rising support by his followers pushed him to forfeit the bail, leave Philadelphia behind, and begin a new life in New York to share his teachings with receptive audiences alike.