[1][4] After completing his formal education, Sachs taught organic chemistry at Chaminade College School followed by a position as a staff fellow at the National Institutes of Health.
[2] In this role, Sachs discovered mechanosensitive ion channels which are sensors for systems including the senses of hearing, touch, and balance.
[8] In 2012, Sachs and Harvey opened their first-ever headquarters in UB’s New York State Center of Excellence in Bioinformatics and Life Sciences and re-named the company Tonus Therapeutics.
[12] In 2001, Sachs led a research team at UB which found that a chemical isolated from the venom of the Chilean tarantula could calm abnormal rhythms induced in rabbit hearts.
[13] Sachs said the result of this study showed that the protein could herald a new class of compounds that could be targeted at treating the causes, rather than the symptoms, of atrial fibrillation.