He was "known and accepted as an important artist in his field" during his lifetime, and his work had a major impact on how American ecclesiastical stained glass looked around the turn of the 20th century.

[4] Perhaps best known for his work at Tiffany Studios, Wilson also designed windows for at least five other firms, including: Heaton, Butler and Bayne, London, England; Alfred Godwin and Company, Philadelphia, Pennsylvania; Gorham Manufacturing Company, Providence, Rhode Island; The Los Angeles Art Glass Company, Los Angeles, California; and Judson Studios, also in Los Angeles.

He was heavily influenced by the work of the Pre-Raphaelites, and incorporated ecclesiastical subjects in his designs from a young age.

[5][6] He likely joined the firm sometime in 1893, and that same year exhibited one of his designs using Tiffany's name at the World's Columbian Exposition in Chicago, Illinois.

[4][10] Wilson's final commission was for a series of windows to be installed in Garrett Memorial Chapel in Jerusalem, New York.