His parents were Adam Frederich, Count of Trampe (1750-1807) and Gertrud Hoffmand de Poulson (1746–1815).

He became deputy judge at Lolland and Falster from 1800, before making a brief military career in the Danish Army.

[2] In Trondhjem (now Trondheim) he was a member of the Royal Norwegian Society of Sciences and Letters, serving as praeses in 1832 right before his death.

[2] Trampe was married three times: in 1797 to Sophie Frederikke Heinrich (1764–1807); in 1808 to Anna Dorothea Colbjørnsen (1792–1808), who died just five months after the wedding; and in 1810, with Amalia Ulrica Frederike Schmettau (1790–1856).

He was the father of several children, including Adam Johan Frederik Poulsen Trampe, Count of Trampe (1798–1876) who served as County Governor of Nordlands amt and of Nordre Trondhjems amt.