FreeSurfer

FreeSurfer is brain imaging software originally developed by Bruce Fischl, Anders Dale, Martin Sereno, and Doug Greve.

[2] Development and maintenance of FreeSurfer is now the primary responsibility of the Laboratory for Computational Neuroimaging[3] at the Athinoula A. Martinos Center for Biomedical Imaging.

FreeSurfer contains a set of programs with a common focus of analyzing magnetic resonance imaging (MRI) scans of brain tissue.

57,541 copies of the FreeSurfer software package have been registered for use as of April 2022[5] and it is a core tool in the processing pipelines of the Human Connectome Project,[6] the UK Biobank,[7] the Adolescent Brain Cognitive Development Study,[8] and the Alzheimer's Disease Neuroimaging Initiative.

[10] The script calls component programs that organize raw MRI images into formats easily usable for morphometric and statistical analysis.

A screen capture of the FreeView application included in FreeSurfer.
FreeSurfer morphs cortical surfaces onto spheres to aide in inter-subject comparisons.