It can also read many other file formats: TIFF (8,16, 32 bits), JPEG, PDF, AVI, MPEG and QuickTime.

OsiriX is able to receive images transferred by DICOM communication protocol from any PACS or medical imaging modality (STORE SCP - Service Class Provider, STORE SCU - Service Class User, and Query/Retrieve).

[2] A demo version, "OsiriX Lite", still remains available free of charge with some limitations.

[3] The OsiriX project started in 2004 at UCLA with Dr Antoine Rosset and Prof. Osman Ratib.

OsiriX MD is a FDA cleared 510k class II medical device, according to US Food And Drug Regulation CFR21 part 820.