On 30 October 1788, Léopard departed Toulon for a cruise in the Caribbean, under Captain de la Galissoninère.

[1] From 1792, Léopard took part in the Expédition de Sardaigne under Captain Bourdon-Gramont, capturing Carloforte on 8 January 1793.

On 17 February, Léopard ran aground in a storm off Cagliari; after two days trying to refloat her, the crew abandoned the ship and set her on fire after offloading the guns and matériel.

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