Fresnes-Mazancourt (French pronunciation: [fʁɛn mazɑ̃kuʁ]; Picard: Frène-Mazancourt) is a commune in the Somme department in Hauts-de-France in northern France.

The commune is situated in the east of the département, 31 miles (50 km) east of Amiens at the junction of the D45 and N17, about a mile from the A1 and A29 autoroute junction.

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