Born in Halberstadt, Porth came with her parents to the theater in Weimar in 1793 where she married the actor Heinrich Vohs on 29 June 1793.
Vohs was the first actress to impersonate the title role in Schiller's drama Maria Stuart in the world premiere on 14 June 1800 at the Deutsches Nationaltheater and Staatskapelle Weimar.
Through this daughter, Karoline, Vohs is an ancestor of British Prime Minister Boris Johnson.
In 1818 she married in second marriage the Dresden court actor Friedrich August Werdy (1770–1847).
A portrait previously thought to be of Goethe's wife Christiane Vulpius, a chalk drawing by Friedrich Bury from the year 1800, in fact shows Friederike Vohs.