[1] The film stars Margaret Laney as Chloe and Alex Brown as Owen, lifelong best friends and current med school students.

Rounding out their tight-knit group of friends are Anne Peterson as Allison, Jake Alexander as Jeff, Lynn Mancinelli as Shirley, Brendan Bradley as Brad and Rooney Mara as Tara.

Taken off a script originally written by Gorman Bechard in 1999, the film was shopped around that summer under the title Fuck Buddies to every major studio in Hollywood.

Inevitably, the script was put on the back burner until Bechard started looking for a lighter follow-up to his extremely dark 2005 feature You Are Alone.

In 2006 Bechard teamed with writing partner Ashley McGarry and they began to rewrite the film, changing the title to Friends (with benefits) and casting Margaret Laney in the lead role.