It is located on 41 acres across two campuses in Wynnewood, a community in Lower Merion Township, Pennsylvania in the Philadelphia metropolitan area.

The main house of the estate, constructed in 1862, remains and serves as the administrative building of the school and an architectural focal point of the campus.

[9] In 2022, Friends’ Central converted the former Rex Gymnasium into Phase I of the school's new Center for Innovation and Design (CID).

This report also indicated that Friends' Central had a student-faculty ratio of 9:1, yearly high school tuition of $25,400 and that 100% of the 93 students in the senior class went on to a four-year college.

In the middle and upper school, students must take three courses concerning the history of the Society of Friends and the central philosophies of Quakerism from a non-religious perspective.

[11] Friends' Central has strong baseball, swimming, girls' track, boys' tennis, basketball, and wrestling programs.