Frullania asagrayana is a reddish-brown species of liverwort in the family Frullaniaceae that grows in eastern North America.

Frullania asagrayana was first described in 1842 by Camille Montagne, a French bryologist and mycologist, and named after the American botanist Asa Gray.

asagrayana until 1987, when an international research team at Southern Illinois University used a variety of morphological, chemical, and genetic markers to determine that the four subspecies of Frullania tamarisci were in fact separate species.

[1] Frullania asagrayana is reddish-brown in colour, and grows closely attached to its substrate.

[2] The endangered lichen Erioderma pedicellatum, which is a symbiosis between an ascomycete fungus and a cyanobacterium, seems to only be able to grow in association with Frullania asagrayana.