It was formed in 1951 as Phthiotis-Phocis Union (Ένωση Φθιωτιδοφωκίδας, Enossi Phthiotidophokidas) and included teams from Phthiotis and the neighbouring prefectures of Phocis and Evrytania.

The Phocis FCA was formed in the 1985–86 season and later its organization in Evrytania was created in 1990.

Its offices and headquarters is located at Othonos Street in the city of Lamia, in People's Square.

All clubs from the Evrytania prefecture split from Phthiotis and formed their own association.

Cup winner in Fthiotida in 2012,[3] was achieved by Aris Agios Konstantinos (for the first time in the association).