She was born in Futamata, Iwata-gun, Shizuoka Prefecture (currently, Nimata Town, Tenryu Ward, Hamamatsu City).
Akino then went to Kyoto to learn Japanese-style painting (Nihonga), under the guidance of Suisho Nishiyama.
The following year, she became an assistant professor at Kyoto City University of Arts.
When she was 53 years old, Akino was invited by India's Visva-Bharati University to be a visiting professor.
Akino visited India several times, painting the country's landscapes, buildings and peoples.