It is also used to prevent infections in people with weak immune systems, including those with neutropenia due to cancer chemotherapy, transplant patients, and premature babies.
Its mechanism of action involves interfering with synthesis of the fungal cell membrane.
Itraconazole (R51211), invented in 1984, is a triazole fungistatic antifungal agent prescribed to patients with fungal infections.
The mechanism of action of itraconazole is the same as the other azole antifungals: it inhibits the fungal-mediated synthesis of ergosterol.
Sodium benzoate and potassium sorbate are both examples of fungistatic substances that are widely used in the preservation of food and beverages.