Fylakio (Greek: Φυλάκιο) is a village in the Evros regional unit of northeast Greece.

It is located on the right bank of the river Ardas, about halfway between Ivaylovgrad (Bulgaria) and Edirne (Turkey).

Towards the end of Ottoman rule, Fylakio's inhabitants were 3/4 Bulgarian and 1/4 Turkish.

Greek refugees from Asia Minor arrived in the village following the end of the war.

South east of the village there is an immigration detention center housing people arrested for illegally crossing the nearby border with Turkey.