He was Kapudan Pasha (grand admiral of the Ottoman Navy) around 1617 and Grand Vizier of the Ottoman Empire from 1619 to 1621.

[1] He was the son of İstanköylü Ahmed Pasha, an Ottoman governor of Tunis.

In 1616 he married Fatma Sultan, a daughter of Sultan Mehmed III by his consort Handan Hatun.

Güzelce Ali Pasha died of inflammation of the gallbladder on 9 March 1621, although there were rumours that Sultan Osman II himself had crept into Ali's tent and strangled him with his own hands due to an ill-advised military campaign on the Polish borderlands.

This Ottoman biographical article is a stub.