These simulations are “computer-based implementations of models whose primary objective is to capture what is known of the anatomical structure and physiological characteristics of the neural system of interest”.

GENESIS works by creating simulation environments for constructing models of neurons or neural systems.

"The synapse is the terminal region of the axon this is where one neuron forms a connection with another and conveys information through the process of synaptic transmission".

The combinatorial possibility could give rise to enormously complex neuronal circuits or network topologies, which might be very difficult to understand".

It's now supported by the Computational Biology Initiative at the University of Texas at San Antonio and is available free along with tutorial guides on its use.

The simulation engine also loads compiled object libraries, reads and writes data files, and interacts with the graphical user interface".

These studies most often occur in lab courses in neural simulation at Caltech and the Marine Biological Laboratory at Woods Hole, Massachusetts.

GENESIS can be used in combination with Yale University’s software called NEURON as a means for scientists to collaborate to construct a physical description of the nervous system.