Variety reported that the decision was meant to partially downplay its ties to Good Morning America by placing a larger emphasis on its hosts, in a similar manner to Today with Hoda & Jenna.

[9] With Haines going on maternity leave after the birth of her third child in June 2019, actress Keke Palmer began filling in as a co-host in the same month.

[11][12] On March 11, 2020, ABC announced that the series along with its morning counterpart would suspend in-studio audiences "for the time being" due to the COVID-19 pandemic in the United States, following a similar decision made by the network and Disney–ABC Domestic Television for their other talk shows, including The View, Live with Kelly and Ryan, and Tamron Hall.

[14] Despite being billed as a temporary replacement for Strahan, Sara & Keke, the program slowly began to evolve into a general daytime newscast in the months that followed.

[15] On August 2, 2020, still absent official confirmation from ABC, Palmer stated on Watch What Happens Live with Andy Cohen that Strahan, Sara & Keke had been canceled.

[19] On December 5, 2022, Holmes and Robach were temporarily placed on leave from the program by ABC News, after it was reported that the co-anchors had an extra-marital romantic relationship.